What is the most common cause of right ventricular hypertrophy

Electrocardiographic Features

Diagnostic criteria
  • Right axis deviation of +110° or more.
  • Dominant R wave in V1 (> 7mm tall or R/S ratio > 1).
  • Dominant S wave in V5 or V6 (> 7mm deep or R/S ratio < 1).
  • QRS duration < 120ms (i.e. changes not due to RBBB).
Supporting criteria
  • Right atrial enlargement (P pulmonale).
  • Right ventricular strain pattern = ST depression / T wave inversion in the right precordial (V1-4) and inferior (II, III, aVF) leads.
  • S1 S2 S3 pattern = far right axis deviation with dominant S waves in leads I, II and III.
  • Deep S waves in the lateral leads (I, aVL, V5-V6).
Other abnormalities caused by RVH
  • Right bundle branch block (complete or incomplete).

ECG Pearl

There are no universally accepted criteria for diagnosing RVH in the presence of RBBB; the standard voltage criteria do not apply. 

However, the presence of incomplete / complete RBBB with a tall R wave in V1, right axis deviation of +110° or more and supporting criteria (such as RV strain pattern or P pulmonale) would be considered suggestive of RVH.

Causes

  • Pulmonary hypertension
  • Mitral stenosis
  • Pulmonary embolism
  • Chronic lung disease (cor pulmonale)
  • Congenital heart disease (e.g. Tetralogy of Fallot, pulmonary stenosis)
  • Arrhythmogenic right ventricular cardiomyopathy

ECG Examples

Example 1

Typical appearance of RVH:

  • Right axis deviation (+150 degrees).
  • Dominant R wave in V1 (> 7 mm tall; R/S ratio > 1)
  • Dominant S wave in V6 (> 7 mm deep; R/S ratio < 1).
  • Right ventricular strain pattern with ST depression and T-wave inversion in V1-4.
Example 2

  • Right axis deviation (+150 degrees)
  • P pulmonale (P wave in lead II > 2.5 mm)
  • Incomplete RBBB
  • Right ventricular strain pattern with T-wave inversion and ST depression in the right precordial (V1-3) and inferior (II, III, aVF) leads.

This ECG was originally posted by Johnson Francis on Cardiophile.org.

Example 4

Right ventricular hypertrophy in a patient with arrhythmogenic right ventricular cardiomyopathy (ARVC):

  • Right axis deviation.
  • R/S ratio in V1 > 1
  • Right ventricular strain pattern with T-wave inversion and ST depression in the right precordial (V1-3) and inferior (II, III, aVF) leads.

This ECG was originally posted by Jayachandran Thejus on the website HeartPearls.com.

  • Right ventricular strain.
  • The ECG in pulmonary embolism.
  • The ECG in chronic lung disease.
  • Left ventricular hypertrophy.

References

  • Harrigan RA, Jones K. ABC of clinical electrocardiography. Conditions affecting the right side of the heart. BMJ. 2002 May 18;324(7347):1201-4. Review. PMID: 12016190
Advanced Reading

Online

  • Wiesbauer F, Kühn P. ECG Yellow Belt online course: Become an ECG expert. Medmastery
  • Wiesbauer F, Kühn P. ECG Blue Belt online course: Learn to diagnose any rhythm problem. Medmastery
  • Rawshani A. Clinical ECG Interpretation ECG Waves
  • Smith SW. Dr Smith’s ECG blog.

Textbooks

  • Mattu A, Tabas JA, Brady WJ. Electrocardiography in Emergency, Acute, and Critical Care. 2e, 2019
  • Brady WJ, Lipinski MJ et al. Electrocardiogram in Clinical Medicine. 1e, 2020
  • Straus DG, Schocken DD. Marriott’s Practical Electrocardiography 13e, 2021
  • Hampton J. The ECG Made Practical 7e, 2019
  • Grauer K. ECG Pocket Brain (Expanded) 6e, 2014
  • Brady WJ, Truwit JD. Critical Decisions in Emergency and Acute Care Electrocardiography 1e, 2009
  • Surawicz B, Knilans T. Chou’s Electrocardiography in Clinical Practice: Adult and Pediatric 6e, 2008
  • Mattu A, Brady W. ECG’s for the Emergency Physician Part I 1e, 2003 and Part II
  • Chan TC. ECG in Emergency Medicine and Acute Care 1e, 2004
  • Smith SW. The ECG in Acute MI. 2002 [PDF]
LITFL Further Reading
  • ECG Library Basics – Waves, Intervals, Segments and Clinical Interpretation
  • ECG A to Z by diagnosis – ECG interpretation in clinical context
  • ECG Exigency and Cardiovascular Curveball – ECG Clinical Cases
  • 100 ECG Quiz – Self-assessment tool for examination practice
  • ECG Reference SITES and BOOKS – the best of the rest

ECG LIBRARY

Electrocardiogram

Ed Burns

Emergency Physician in Prehospital and Retrieval Medicine in Sydney, Australia. He has a passion for ECG interpretation and medical education | ECG Library |

Robert Buttner

MBBS (UWA) CCPU (RCE, Biliary, DVT, E-FAST, AAA) Adult/Paediatric Emergency Medicine Advanced Trainee in Melbourne, Australia. Special interests in diagnostic and procedural ultrasound, medical education, and ECG interpretation. Editor-in-chief of the LITFL ECG Library. Twitter: @rob_buttner

Can right ventricular hypertrophy be cured?

Treatment also aims to reduce or stop the thickening of the walls of the right ventricle. Currently, there is no treatment to reverse the thickening of these walls completely, although ACE inhibitors have been shown to help. Preventing right ventricular hypertrophy from getting worse is possible in many cases.

What is the treatment for right ventricular hypertrophy?

The treatment of right ventricular hypertrophy depends on the underlying cause. If pulmonary atrial hypertension is the cause, you may need medication to help relax your pulmonary artery, such as sildenafil (Revatio). Other medications your doctor might prescribe to improve heart function include: ACE inhibitors.

Can right ventricular hypertrophy be benign?

RVH can be benign and have little impact on day-to-day life or it can lead to conditions such as heart failure, which has a poor prognosis.

What would you most likely see in right ventricular hypertrophy?

Right ventricular hypertrophy causes large R-waves in right-sided chest leads and deeper S-waves in left-sided leads.

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