OverviewWhat is small cell lung cancer?Small cell lung cancer is a rare fast-growing lung cancer. Small cell lung cancer can affect anyone, but it typically affects people who have a long history of tobacco use, specifically smoking cigarettes. Healthcare providers can cure some people if the disease is found early; for others, they can help them live longer. The only way to prevent small cell lung cancer is to stop smoking. Show
How common is this condition?Overall, about 57 in 100,000 people in the U.S. develop lung cancer. Small cell lung cancer represents about 15% of those cancer diagnoses. It’s less common than non-small cell lung cancer. How does small cell lung cancer affect my body?Small cell lung cancer starts when healthy cells in your lungs mutate or change into cancerous cells. These cells then divide and multiply uncontrollably. Eventually, the cancerous cells clump together in masses (tumors) in your lungs. These tumors may shed cancer cells that your blood or lymph pick up and carry throughout your body. (Lymph is fluid that travels through your body to your lymph nodes.) Small cell lung cancer typically spreads to:
Once the cells have spread, they may create new cancerous tumors in your lymph nodes and organs. Small cell lung cancer may also cause fluid to build up in your lungs or in the space around your lungs. It can make your lung collapse by pushing air out of your lung. This is called a pleural effusion. There are two types of small cell lung cancer:
Symptoms and CausesWhat are the symptoms of small cell lung cancer?Small cell lung cancer that hasn’t spread rarely causes symptoms. When symptoms happen, they may include:
Many of these symptoms are similar to other less serious conditions. Having one or more of these symptoms isn’t a sign you have small cell lung cancer. That said, if you smoke or you used to smoke and you notice these types of symptoms, talk to a healthcare provider. They’ll evaluate your situation and recommend any next steps. What causes small cell lung cancer?While anyone can get lung cancer, people who smoke, used to smoke or who are exposed to tobacco smoke (second-hand smoke) have an increased risk of developing small cell lung cancer. Other risk factors include:
Diagnosis and TestsHow do healthcare providers diagnose small cell lung cancer?Chest X-rays are typically the first step to evaluate someone for any type of lung cancer. If images show suspicious spots on your lung, a healthcare provider may order one or more of these diagnostic tests:
What are the stages of small cell lung cancer?Healthcare providers use a two-stage system to diagnose the spread of small cell lung cancer. This information also helps guide treatment. The two stages of small cell lung cancer are:
Management and TreatmentWhat are treatments for small cell lung cancer?Treatment depends on many factors including your age, overall health and cancer stage. Treatment options include:
What happens if I can’t have surgery and other treatments aren’t making a difference?There are options your healthcare provider may recommend and you may want to consider, such as:
PreventionHow do I reduce my risk of developing this condition?Avoiding tobacco is the best way to prevent small cell lung cancer. If you currently smoke tobacco, try to quit as soon as possible. Regardless of how old you are or how long you’ve been smoking, your lungs begin to heal as soon as you stop. Giving your lungs a chance to heal reduces your risk of developing small cell lung cancer. If you smoke tobacco and want to quit, ask a healthcare provider about smoking cessation treatment and programs. What about lung cancer screening tests?Unlike other types of lung cancer, there isn’t a screening test for small cell lung cancer. What else can I do to reduce my risk?These steps may also help:
Outlook / PrognosisWhat is the prognosis for small cell lung cancer?Small cell lung cancer is a very aggressive illness. Without treatment, most people with small cell lung cancer die a few months after they’re diagnosed. Healthcare providers can treat small cell lung cancer, but the disease often comes back. A 2020 study showed more than 50% of people treated for small cell lung cancer had a recurrence, meaning the cancer came back. According to 2020 data, about 7% of all people with small cell lung cancer were alive five years after diagnosis. Many factors affect small cell lung cancer prognoses:
There’s no question that the prognoses for small cell lung cancer are grim. It’s important to remember a prognosis is what may happen, not what will happen. If you have small cell lung cancer and want to know your prognosis, ask your healthcare provider to explain what you may expect. What is the survival rate?Survival rates are estimates based on the experiences of groups of people. About 70% of people with small cell lung cancer aren’t diagnosed until after the cancer has spread (extensive-stage small cell lung cancer.) These people have fewer treatment options. According to 2020 data:
Remember — just like prognoses, survival rates are estimates based on the experiences of groups of people. What’s happened to other people may not apply in your situation. Living WithI have small cell lung cancer. How do I take care of myself?Surgery and other cancer treatment can be physically challenging. You may feel exhausted after completing treatment. Here are some things you can do to stay strong through treatment:
What questions should I ask my healthcare provider?If you have small cell lung cancer, you may want to ask your healthcare provider:
Frequently Asked QuestionsWhat is the difference between non-small cell lung cancer and small cell lung cancer?There are several differences:
A note from Cleveland Clinic More people with small cell lung cancer are living longer thanks to early cancer screenings and newer treatments. Healthcare providers have treatments to help people to live longer and with a good quality of life and that may cure some people Tobacco use causes small cell lung cancer. If you smoke, try to stop. It’s never too late to stop smoking, even if you already have lung cancer. Ask your healthcare provider for help finding smoking cessation programs. Is limited stage small cell lung cancer curable?Although small cell lung cancer is an aggressive disease, it responds well to initial chemotherapy and radiation. The goal of treatment for people with limited-stage small cell lung cancer is cure, which is achieved in 20 to 25 percent of patients.
What is the survival rate for limited small cell lung cancer?For people with localized SCLC, which means the cancer has not spread outside of the lung, the overall 5-year survival rate is 27%. For regional SCLC, which means the cancer has spread outside of the lung to nearby areas, the 5-year survival rate is 16%.
Is small cell lung cancer fatal?Outlook (Prognosis)
SCLC is very deadly. Not many people with this type of cancer are still alive 5 years after diagnosis. Treatment can often prolong life for 6 to 12 months, even when the cancer has spread. In rare cases, if SCLC is diagnosed early, treatment may result in a long-term cure.
Is small cell lung cancer considered terminal?People with small-cell lung cancer in the advanced stage cannot be cured. They usually survive less than one year. Treatment may be moderately successful for people with the limited-stage disease. However, even with the limited-stage disease, the median survival time is less than two years.
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