Icd 10 code for prostate cancer metastatic to multiple sites

Resources

Taiho Oncology Patient Support™

A one-stop source for the customized support patients need

Dosage

Access & Reimbursement

Designed to simplify patient access to LONSURF

We know getting patients access to LONSURF® (FTD/TPI) tablets is a critical step in their treatment. We strive to make this process as simple as possible with:

Help Accessing Prescribed Treatment

Assistance with insurance, including benefits verification, prior authorization, appeals support, and more.

$0 Co-Pay Financial Assistance*

Identifying options for financial support based on current coverage.

Nurse Support

One-on-one educational support for patients, available via opt-in.

*For commercially insured, eligible patients.

How to enroll

We offer 3 convenient ways to enroll in the Taiho Oncology Patient Support™ Services to help simplify treatment access:

Download, Print,
and Upload

Download and fill in the Enrollment Form and print it out to complete.

Upload the completed form to the HCP Portal.

Or

Download, Print,
and Fax

Download and fill in the Enrollment Form and print it out to complete.

Fax the completed form to
1-844-287-2559.

Or

By Phone

Call 1-844-TAIHO-4U
(1-844-824-4648) for help
with enrollment.

Financial Support

Commercially insured, eligible patients can enroll in the Co-Pay Assistance Program to potentially reduce out-of-pocket expenses to $0.

Get co-pay card now!

Access and reimbursement support

• Benefits verifications (BVs) to determine and report patients' insurance coverage for LONSURF
• Prior authorization assistance to meet payer requirements
• Appeals assistance for denied prior authorizations

Specialty pharmacy prescription coordination

• Prescription triage
• Coordination with the in‑network specialty pharmacy, self‑dispensing practice, or hospital outpatient pharmacy
• Communicating regularly with patients about their prescription status

Patient Assistance Program

• We research financial assistance opportunities for patients with no or insufficient prescription insurance coverage or insufficient resources to pay for LONSURF. Eligible patients may receive LONSURF at no cost based on assistance, financial, and medical criteria

Alternate funding support

• We refer eligible, publicly insured patients (eg, Medicare, Medicaid) to third-party organizations for co‑pay assistance

Nurse support upon request

• Our nurse support services are available as needed to support patient care, including education about the importance of taking the medicine as prescribed and refill reminders. We will quickly verify each patient's LONSURF coverage and help them get access to the LONSURF treatment they have been prescribed

*Restrictions and eligibility: Offer valid in the US, Puerto Rico, and US territories only. Only valid for patients with private insurance. Offer not valid for prescriptions reimbursed under Medicaid, a Medicare drug benefit plan, Tricare, or other federal or state programs (such as medical assistance programs). If the patient is eligible for drug benefits under any such program, this offer is not valid and the patient cannot use this offer. By presenting or accepting this benefit, patient and pharmacist agree not to submit claim for reimbursement under the above programs. Patient further agrees to comply with any and all terms of his or her health insurance contract requiring notification to his or her payer of the existence and/or value of this offer. It is illegal to or offer to sell, purchase, or trade this benefit. Maximum reimbursement limits apply; patient out-of-pocket expense may vary. Taiho Oncology, Inc., reserves the right to rescind, revoke, or amend this offer at any time without notice.

Professional Resources & Tools

Dosage Sheet

Reminds patients of their active treatment days and their morning and evening doses. Print a Dosage Sheet and then fill it out with your patient.

LONSURF Dosage Calculator

Calculate your patients’ personalized dosage and create personalized dosing calendars.

LONSURF: What to Expect

Counselling tips–including possible side effects and health outcomes–to discuss with your patients while they are taking LONSURF.

My LONSURF Story: Pharmacist Perspective

Latha Radhakrishnan, PharmD, BCPS, BCOP a clinical pharmacist shares a real-life perspective on dosing treatment with LONSURF.

My LONSURF Story: Nurse Perspective

Alice Beers, BSN, OCN, RN-BC, an oncology nurse gives her personal perspective on treatment with LONSURF.

Patient Resources & Tools

LONSURF Patient Starter Kit

Contains useful resources and tools to help your patients start and stay on LONSURF, including a:

LONSURF Patient Starter Kit

Contains useful resources and tools to help your patients start and stay on LONSURF, including a:

• Patient Brochure Offers information on how LONSURF can help, how it is taken, tips on managing common side effects, and services that may be able to help with medication costs
• Caregiver Brochure Provides an overview of LONSURF and how it is taken, useful tips that may help manage common side effects, and strategies to help caregivers take care of themselves and their loved one
• Thermometer Encourages patients to check for fever while taking LONSURF
• LONSURF Pillboxes Designed to help patients organize their LONSURF tablets
• Treatment Calendar Allows patients to track their dosing habits and record side effects or questions

To request a Patient Starter Kit, you can:

Patient Brochure

Offers information on how LONSURF can help, how it is taken, tips on managing common side effects, and services that may be able to help with medication costs.

Caregiver Brochure

Provides an overview of LONSURF and how it is taken, useful tips that may help manage common side effects, and strategies to help caregivers take care of themselves and their loved one.

Side Effect Management Tool

Located on the LONSURF Patient website, this interactive tool outlines useful tips to help patients manage some of the most common side effects associated with LONSURF.

Personalized Treatment Calendar

Located on the LONSURF Patient website, this interactive tool helps you and your patients create a personalized treatment calendar to ensure they understand their dosing schedule.

LONSURF® (FTD/TPI) Tablets Coding Information

The following 2021 ICD-10 codes are effective from October 1, 2021 through September 30, 2022. The diagnostic codes contained in this section are designed to provide important reimbursement information that will be helpful for your practice. ICD codes continually change, so it is recommended that you consult your ICD-10 code book or contact the payer for coding and billing guidance.

• Metastatic colorectal cancer
• Metastatic gastric cancer

Diagnosis codes for LONSURF use in metastatic colorectal cancer1

This information is not intended as coverage or coding advice and does not guarantee reimbursement. You should verify the appropriate reimbursement information for services or items you provide. Each healthcare professional is responsible for ensuring all coding is accurate and appropriate.

Diagnosis codes for LONSURF use in metastatic gastric cancer1

This information is not intended as coverage or coding advice and does not guarantee reimbursement. You should verify the appropriate reimbursement information for services or items you provide. Each healthcare professional is responsible for ensuring all coding is accurate and appropriate.

FTD/TPI = trifluridine/tipiracil

INDICATIONS

INDICATIONS

LONSURF is indicated for the treatment of adult patients with metastatic colorectal cancer previously treated with fluoropyrimidine‑, oxaliplatin‑ and irinotecan‑based chemotherapy, an anti‑VEGF biological therapy, and if RAS wild type, an anti‑EGFR therapy.

LONSURF is indicated for the treatment of adult patients with metastatic gastric or gastroesophageal junction adenocarcinoma previously treated with at least two prior lines of chemotherapy that included a fluoropyrimidine, a platinum, either a taxane or irinotecan, and if appropriate, HER2/neu‑targeted therapy.

Indications and Important Safety Information +

INDICATIONS

LONSURF is indicated for the treatment of adult patients with metastatic colorectal cancer previously treated with fluoropyrimidine‑, oxaliplatin‑ and irinotecan‑based chemotherapy, an anti‑VEGF biological therapy, and if RAS wild type, an anti‑EGFR therapy.

LONSURF is indicated for the treatment of adult patients with metastatic gastric or gastroesophageal junction adenocarcinoma previously treated with at least two prior lines of chemotherapy that included a fluoropyrimidine, a platinum, either a taxane or irinotecan, and if appropriate, HER2/neu‑targeted therapy.

IMPORTANT SAFETY INFORMATION

WARNINGS AND PRECAUTIONS

Severe Myelosuppression: LONSURF caused severe and life‑threatening myelosuppression (Grade 3‑4) consisting of neutropenia (38%), anemia (18%), thrombocytopenia (5%), and febrile neutropenia (3%). Two patients (0.2%) died due to neutropenic infection. A total of 12% of LONSURF‑treated patients received granulocyte‑colony stimulating factors. Obtain complete blood counts prior to and on day 15 of each cycle of LONSURF and more frequently as clinically indicated. Withhold LONSURF for febrile neutropenia, absolute neutrophil count less than 500/mm3, or platelets less than 50,000/mm3. Upon recovery, resume LONSURF at a reduced dose as clinically indicated.

Embryo‑Fetal Toxicity: LONSURF can cause fetal harm when administered to a pregnant woman. Advise pregnant women of the potential risk to the fetus. Advise females of reproductive potential to use effective contraception during treatment and for at least 6 months after the final dose.

USE IN SPECIFIC POPULATIONS

Lactation: It is not known whether LONSURF or its metabolites are present in human milk. There are no data to assess the effects of LONSURF or its metabolites on the breast‑fed infant or the effects on milk production. Because of the potential for serious adverse reactions in breast‑fed infants, advise women not to breastfeed during treatment with LONSURF and for 1 day following the final dose.

Male Contraception: Because of the potential for genotoxicity, advise males with female partners of reproductive potential to use condoms during treatment with LONSURF and for at least 3 months after the final dose.

Geriatric Use: Patients 65 years of age or over who received LONSURF had a higher incidence of the following compared to patients younger than 65 years: Grade 3 or 4 neutropenia (46% vs 32%), Grade 3 anemia (22% vs 16%), and Grade 3 or 4 thrombocytopenia (7% vs 4%).

Hepatic Impairment: Do not initiate LONSURF in patients with baseline moderate or severe (total bilirubin greater than 1.5 times ULN and any AST) hepatic impairment. Patients with severe hepatic impairment (total bilirubin greater than 3 times ULN and any AST) were not studied. No adjustment to the starting dose of LONSURF is recommended for patients with mild hepatic impairment.

Renal Impairment: No adjustment to the starting dosage of LONSURF is recommended in patients with mild or moderate renal impairment (CLcr of 30 to 89 mL/min). Reduce the starting dose of LONSURF for patients with severe renal impairment (CLcr of 15 to 29 mL/min) to a recommended dosage of 20 mg/m2.

ADVERSE REACTIONS

Most Common Adverse Drug Reactions in Patients Treated With LONSURF (≥5%): The most common adverse drug reactions in LONSURF‑treated patients vs placebo‑treated patients with mCRC, respectively, were asthenia/fatigue (52% vs 35%), nausea (48% vs 24%), decreased appetite (39% vs 29%), diarrhea (32% vs 12%), vomiting (28% vs 14%), infections (27% vs 16%), abdominal pain (21% vs 18%), pyrexia (19% vs 14%), stomatitis (8% vs 6%), dysgeusia (7% vs 2%), and alopecia (7% vs 1%). In metastatic gastric cancer or gastroesophageal junction (GEJ), the most common adverse drug reactions, respectively were, nausea (37% vs 32%), decreased appetite (34% vs 31%), vomiting (25% vs 20%), infections (23% vs 16%) and diarrhea (23% vs 14%).

Pulmonary emboli occurred more frequently in LONSURF‑treated patients compared to placebo: in mCRC (2% vs 0%) and in metastatic gastric cancer and GEJ (3% vs 2%).

Interstitial lung disease (0.2%), including fatalities, has been reported in clinical studies and clinical practice settings in Asia.

Laboratory Test Abnormalities in Patients Treated With LONSURF: The most common laboratory test abnormalities in LONSURF‑treated patients vs placebo‑treated patients with mCRC, respectively, were anemia (77% vs 33%), neutropenia (67% vs 1%), and thrombocytopenia (42% vs 8%). In metastatic gastric cancer or GEJ, the test abnormalities, respectively, were neutropenia (66% vs 4%), anemia (63% vs 38%), and thrombocytopenia (34% vs 9%).

Please see full Prescribing Information.

Indications and Important Safety Information

INDICATIONS

LONSURF is indicated for the treatment of adult patients with metastatic colorectal cancer previously treated with fluoropyrimidine‑, oxaliplatin‑ and irinotecan‑based chemotherapy, an anti‑VEGF biological therapy, and if RAS wild type, an anti‑EGFR therapy.

LONSURF is indicated for the treatment of adult patients with metastatic gastric or gastroesophageal junction adenocarcinoma previously treated with at least two prior lines of chemotherapy that included a fluoropyrimidine, a platinum, either a taxane or irinotecan, and if appropriate, HER2/neu‑targeted therapy.

IMPORTANT SAFETY INFORMATION

WARNINGS AND PRECAUTIONS

Severe Myelosuppression: LONSURF caused severe and life‑threatening myelosuppression (Grade 3‑4) consisting of neutropenia (38%), anemia (18%), thrombocytopenia (5%), and febrile neutropenia (3%). Two patients (0.2%) died due to neutropenic infection. A total of 12% of LONSURF‑treated patients received granulocyte‑colony stimulating factors. Obtain complete blood counts prior to and on day 15 of each cycle of LONSURF and more frequently as clinically indicated. Withhold LONSURF for febrile neutropenia, absolute neutrophil count less than 500/mm3, or platelets less than 50,000/mm3. Upon recovery, resume LONSURF at a reduced dose as clinically indicated.

Embryo‑Fetal Toxicity: LONSURF can cause fetal harm when administered to a pregnant woman. Advise pregnant women of the potential risk to the fetus. Advise females of reproductive potential to use effective contraception during treatment and for at least 6 months after the final dose.

USE IN SPECIFIC POPULATIONS

Lactation: It is not known whether LONSURF or its metabolites are present in human milk. There are no data to assess the effects of LONSURF or its metabolites on the breast‑fed infant or the effects on milk production. Because of the potential for serious adverse reactions in breast‑fed infants, advise women not to breastfeed during treatment with LONSURF and for 1 day following the final dose.

Male Contraception: Because of the potential for genotoxicity, advise males with female partners of reproductive potential to use condoms during treatment with LONSURF and for at least 3 months after the final dose.

Geriatric Use: Patients 65 years of age or over who received LONSURF had a higher incidence of the following compared to patients younger than 65 years: Grade 3 or 4 neutropenia (46% vs 32%), Grade 3 anemia (22% vs 16%), and Grade 3 or 4 thrombocytopenia (7% vs 4%).

Hepatic Impairment: Do not initiate LONSURF in patients with baseline moderate or severe (total bilirubin greater than 1.5 times ULN and any AST) hepatic impairment. Patients with severe hepatic impairment (total bilirubin greater than 3 times ULN and any AST) were not studied. No adjustment to the starting dose of LONSURF is recommended for patients with mild hepatic impairment.

Renal Impairment: No adjustment to the starting dosage of LONSURF is recommended in patients with mild or moderate renal impairment (CLcr of 30 to 89 mL/min). Reduce the starting dose of LONSURF for patients with severe renal impairment (CLcr of 15 to 29 mL/min) to a recommended dosage of 20 mg/m2.

ADVERSE REACTIONS

Most Common Adverse Drug Reactions in Patients Treated With LONSURF (≥5%): The most common adverse drug reactions in LONSURF‑treated patients vs placebo‑treated patients with mCRC, respectively, were asthenia/fatigue (52% vs 35%), nausea (48% vs 24%), decreased appetite (39% vs 29%), diarrhea (32% vs 12%), vomiting (28% vs 14%), infections (27% vs 16%), abdominal pain (21% vs 18%), pyrexia (19% vs 14%), stomatitis (8% vs 6%), dysgeusia (7% vs 2%), and alopecia (7% vs 1%). In metastatic gastric cancer or gastroesophageal junction (GEJ), the most common adverse drug reactions, respectively were, nausea (37% vs 32%), decreased appetite (34% vs 31%), vomiting (25% vs 20%), infections (23% vs 16%) and diarrhea (23% vs 14%).

Pulmonary emboli occurred more frequently in LONSURF‑treated patients compared to placebo: in mCRC (2% vs 0%) and in metastatic gastric cancer and GEJ (3% vs 2%).

Interstitial lung disease (0.2%), including fatalities, has been reported in clinical studies and clinical practice settings in Asia.

Laboratory Test Abnormalities in Patients Treated With LONSURF: The most common laboratory test abnormalities in LONSURF‑treated patients vs placebo‑treated patients with mCRC, respectively, were anemia (77% vs 33%), neutropenia (67% vs 1%), and thrombocytopenia (42% vs 8%). In metastatic gastric cancer or GEJ, the test abnormalities, respectively, were neutropenia (66% vs 4%), anemia (63% vs 38%), and thrombocytopenia (34% vs 9%).

Please see full Prescribing Information.

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